The symbiotic bacteria of the mangrove fruit, Xylocarpus sp., have the potential to act as antibacterial and antifungal agents. The research objective is to determine the possibility of producing symbiotic bacteria for the cosmetic bioindustry. Isolate Alcaligenes aquatilis (Isolate X1.63), Sinomicrobium oceani (Isolate X2.52), S. oceani (Isolate X1.54), Pseudomonas khazarica (Isolate X1.64), S. oceani (Isolate X1.53), and Proteus mirabilis (Isolate X1.65) bacteria were used as samples and tested against pathogenic bacteria and pathogenic fungi. Then, a cream was prepared using symbiotic bacteria as the main ingredient with different concentrations for subsequent testing on mouse skin over 14 days. Finally, it was analyzed using histological methods. Hair follicle growth ability was observed at various concentrations of the cream. Specifically, the consortium bacterial cream shows superior efficacy compared to other treatments. Testing bacterial extract as a cream formulation can be an alternative treatment for alopecia (baldness). The research findings concluded that the symbiotic bacteria of Xylocarpus sp. mangrove fruit have the potential to be used as a material for the cosmetic bioindustry. This is because, in addition to having antibacterial and antifungal properties, they also demonstrate potential for use as a hair cream product for treating alopecia.
Key words: Antibacterial, antifungal, cosmetics, histology, mangrove
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