THE IMPACT OF VACCINATION AGAINST SARS-CoV-2 INFECTION ON VESTIBULAR FUNCTION AND CENTRAL COMPENSATION
Oğuz Yılmaz,Berna Özge Mutlu,Handan Yaman,Cem Yeral,Oğulcan Gündoğdu,Dilara Bayazıt,Yıldırım Ahmet Bayazıt.
Abstract
Objective: The aim of this study was to evaluate the effects of SARS-CoV-2 vaccines on vestibular system. In addition, in this study we aimed to investigate the possible protective effects of vaccination on the vestibular system in people who recovered Covid-19.
Methods: Totally, 77 subjects were divided into four groups, and evaluated using computerized dynamic posturography (CDP), vestibular evoked myogenic potentials (VEMPs) and video head impulse test (v-HIT). The groups were as follows;
Group 1; who had SARS-CoV-2 infection at least one year ago and have not been vaccinated at all. c
Group 2; who had SARS-CoV-2 infection at least one year ago and were vaccinated 5 times (2 doses of Sinovac and 3 doses of Biontech).
Group 3; who had no known SARS-CoV-2 infection, and were vaccinated 5 times (2 doses of Sinovac and 3 doses of Biontech).
Group 4; who had no known SARS-CoV-2 infection, and have not been vaccinated at all.
Results: The SOT values of (Covid-Vaccine-) group were better than the (Covid+Vaccine-) group (p=0.001), and no other significant difference was found between the groups (p>0.05). The v-HIT gains of the groups were not significantly different (p>0.05). On o-VEMPs, there was elongation in the N1 and P1 latencies in (Covid+Vaccine-) group compared to (Covid-Vaccine+) group. The amplitudes decreased in (Covid+Vaccine-) compared to (Covid-Vaccine-) (p
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