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Total antioxidant stress and total oxidant stress levels in geriatric patients with open heart

Zinet Asuman Arslan Onuk, Bilge Karsli, Barıs Arslan.




Abstract

The aim at this study is to compare the association with oxidative stress with the patients over and below the age of 65, who underwent an open heart surgery. In our prospective and a single-center study, 45 patients, undergoing an elective isolated on-pump CABG and heart-valve surgery, were included. The patients were divided into two groups, including Group I (at the age of 65 over) and Group II (at the age of 65 and below). The serum total oxidant status (TOS) and total antioxidant status (TAS) values were assessed in the patients, by taking blood at the first hour before and after the pump. There is no statisti-cally significant diffrences between preoperative and postoperative TAS and TOS values within the groups. However, the postoperative TOS value in Group I is statistically greater than Group II. TAS and TOS in organism is affected by many factors. Futher controlled studies are needed on this topic.

Key words: Heart surgery, total antioxidant stress, total oxidant stress, oxidative stress






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