The present clinical study was conducted to evaluate the efficacy of different therapeutic regimens along with 10% zinc-sulfate footbath for the treatment of acute foot rot in adult sheep. A total of 104 adult sheep of both sexes (70 females and 34 males) were presented to the Teaching Veterinary Clinical Complex, Faculty of Veterinary Sciences and Animal Husbandry during the period April 2013 to May 2014. Foot rot in the sheep was confirmed based on clinical and physical analysis. The sheep were divided into four equal groups; Group I, II, III, and IV. The animals of the Group I, II and IV were treated with a mixture of amoxicillin and cloxacillin dosed at 15 mg/kg body weight (b.wt.) through intramuscular (IM) route, oxytetracycline dosed at 20 mg/kg b.wt., IM, and enrofloxacin dosed at 5 mg/kg b.wt., IM, respectively. The animals of Group III were treated with gamma benzene hexachloride cream. Along with the above treatments, the animals of all four groups were given footbath with 10% zinc-sulfate. The mean recovery time (days) recorded was lowest in group II (3.83±0.64) followed by Group I (4.17±0.31), Group IV (4.38±0.0.79) and Group III (5.67±0.98), respectively. The mean±SE values of rectal temperature and ruminal motility recorded before and after the treatment showed significant (p
Key words: Antibiotics, Foot rot, Footbath, Lameness, Sheep
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