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A Retrospective Study of Various Iron Preparations Oral Administration in Pregnant Women with Iron Deficiency Anemia

Bouschanetzis Constantinos, Anastasia Bothou, Efthimis Oikonomou, Demetris Kiriakou, Stavroula Papanikolopoulou, Spyridon Michalopoulos, Georgios Iatrakis, Konstantinos Nikolettos, Grigorios Trypsiannis, Nikolaos Nikolettos, Panagiotis Tsikouras.



Abstract
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Background: During pregnancy anemia is a common medical condition, with iron deficiency and megaloblastic anemia being the most common. The symptoms range from very mild to severe and if left without proper medical treatment, there can be serious consequences for both mother and fetus. Objective: The aim of this study was to compare various iron preparations which made in the three trimesters of pregnancy and in the period of delivery regarding the incidence of iron deficiency anemia in pregnant women. Methods: Iron deficiency anemia is diagnosed when hemoglobin levels are below: 13.0 g/dL a) in adult males, b) 12.0 g/dL in non-pregnant women, c) 11.0 g/dL in pregnant women and children 6 months–5 years, and d) 11.5 g/dL in children 5–11 years old. Serum ferritin, transferrin saturation, transferrin receptors and erythrocyte protoporphyrin are used as biochemical markers of iron deficiency. Results: This case-control study was conducted at a Greek university hospital affiliated with Democritus University. About 199 pregnant women who were divided into two groups were included in the study from 01.02.2015 to 31.12.2022. The differential diagnosis of iron deficiency anemia will be made from other forms of hypochromic microcytic anemia. The most frequent pregnancy problem was anemia. The term “Iron Deficiency Anemia” refers to erythropoiesis under conditions of absolute iron deficiency. This presupposes the depletion of iron stores in the body. Iron deficiency anemia or Sideropenic anemia is the most common form of anemia worldwide. Special attention must be given to nutrition during pregnancy. In the current retrospective study, Conclusion: It was evaluated the contribution of various iron preparations substitution during the pregnancy and puerperium.

Key words: Anemia in Pregnancy, Iron deficiency anemia, Sideropenic anemia







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