Background: There has been an increasing prevalence of diabetes worldwide. Diabetic peripheral neuropathy is the most common complication of type I and II diabetes. Peripheral neuropathy is a damage occurring in the nerves due to prolonged higher levels of blood sugar and diabetes. There are various screening tests such as vibration perception threshold (VPT), neuropathy symptom profile, michigan neuropathy screening instrument, neuropathy disability score, and Michigan diabetic neuropathy score. VPT accounts for an easy and accurate identification of diabetic patients, who are at risk, including patients, with early neuropathic deficits. Toronto clinical neuropathy score (TCNS) has been validated as a score for monitoring and diagnosing diabetic peripheral neuropathy.
Aims and Objectives: This study was done to estimate the sensitivity, evaluate specificity, and determine the positive predictive value and negative predictive value of TCNS scoring in diabetic peripheral neuropathy patients considering VPT as the gold standard.
Materials and Methods: In this study, VPT and TCNS were determined in 100 type 2 diabetic subjects with signs and symptoms of peripheral neuropathy.
Results: In this study, it was estimated that TCNS is a reliable measure of distal poly neuropathy with a sensitivity of 95.83%, 100% specificity, positive predictive value of 100%, and negative predictive value of 50%.
Conclusion: From our study, it was found that TCNS is a sensitive indicator of definite clinical neuropathy.
Key words: Diabetes; Vibration Perception Threshold; Toronto Clinical Neuropathy Score
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