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Dermatochalasis: A potential risk factor for cardiovascular diseases

Sumeyra Koprubasi, Mehmet Kay, Emine Altuntas.




Abstract

To examine the cardiac parameters of patients with dermatochalasis by echocardiography to analyze whether there is a relationship between dermatochalasis and cardiac disorders. This prospective comparative study included 132 (57 male, 75 female) patients with dermatochalasis with an average age of 47.09±9.53 years and 77 (34 male, 43 female) healthy controls with an average age of 47.31±4.23 years. Each participant was examined by 2-dimensional, M-mode, and color-flow Doppler, pulsed-wave (PW) Doppler, and tissue Doppler imaging (TDI) echocardiography. In patients with dermatochalasis, PW Doppler transvalvular mitral flow measurements showed higher late diastolic flow velocity (A) but lower early diastolic flow velocity (E) and E/A ratio compared to the control group (p=.056, p=.02, and p=.04, respectively). Similarly, TDI measurements showed lower lateral and septal early diastolic myocardial velocities (E'), and higher lateral and septal late diastolic myocardial velocities (A), and E/E' ratios in patients with dermatochalasis compared to the control group (p=.03, p=.01, p=.09, p=.04, p=.02, and p=.01, respectively). In this study, we discovered that patients with dermatochalasis have abnormal left ventricular diastolic function. It indicates that dermatochalasis may be responsible for subclinical cardiac involvement.

Key words: Dermatochalasis, left ventricular diastolic dysfunction, cardiac involvement, tissue Doppler echocardiography, pulsed-wave Doppler






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