Background: Glaucoma is a chronic progressive optic neuropathy with characteristic optic disk and visual field (VF) changes, high intraocular pressure (IOP) being important risk. Detection and monitoring of optic disk and retinal nerve fiber layer (RNFL) changes is essential in the management of glaucoma.
Aims and Objectives: The objectives of this study were to evaluate the role of RNFL versus optic nerve head (ONH) parameter in diagnosis of the early glaucoma using spectral-domain optical coherence tomography (SD-OCT).
Materials and Methods: This was a comparative study done on patients attending ophthalmology department of our hospital. Sixty patients including 35 early glaucoma as study group and 25 normal patients as control group between age 40 and 80 years were included in the study. Complete ocular examination including IOP, fundoscopy, VFs 30-2 SITA STD, OCT – fast RNFL scan, and fast optic disk scan were done.
Results: Mean age in study group is 58.14 ± 7.3 SD and in control group is 54.16 ± 7.45 SD. Glaucoma group had 25 males and ten females, whereas control group had 18 males and seven females. VF mean deviation in study group was – 2.13 ± 1.33and – 1.24 ± 0.88 in control group. PSD was 2.46± 0.48 in study group and 1.81 ± 0.12 in control group. RNFL parameters in all quadrants and average were statistically significant in study group compared to control group. Excellent RNFL parameters were IRNFL, followed by SRNFL, average RNFL, nasal RNFL, and temporal RNFL. Among ONH parameters, rim volume, disk area, and rim area had better performing index in differentiating normal from the early glaucoma damage.
Conclusion: SD-OCT has ability to differentiate normal from the early glaucoma disks. RNFL thickness parameters were better than ONH parameters.
Key words: Glaucoma; Optic Disk; CD Ratio; Spectral-Domain Optical Coherence Tomography; Retinal Nerve Fiber Layer; Optic Nerve Head
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