The human body’s inability to sustain adequate levels of free radicals leads to oxidative stress on the body. While the human body possesses robust endogenous antioxidant mechanisms, the heightened generation of reactive oxygen species can diminish the efficacy of these protective systems. Hence, the application of exogenous antioxidants may contribute to the mitigation of oxidative stress. A restricted quantity of these pharmaceutical compounds has been subjected to meticulous assessment in controlled clinical trials, although the transdermal liposome formulation demonstrates promise as an antioxidant therapeutic intervention. This review aims to investigate transdermal liposomes as antioxidants through bibliometric analysis using Rstudio and VOSviewer. The data evaluation process involved the utilization of the VOSviewer application and RStudio. Subsequently, 51 articles encompassing 2013– 2023 were employed to compile the ultimate bibliometric dataset. The Anhui University of Chinese Medicine is the most prolific institution, exhibiting remarkable global influence. Caddeo C is identified as the author with the highest publication output, while the article authored by Jeon et al. in 2015, is regarded as the most influential publication. These results are performed to provide a broad understanding of transdermal liposomes as antioxidants.
Key words: Antioxidant, bibliometric, transdermal liposome, PubMed, RStudio, VOSviewer
|