Primer congenital glaucoma is an uncommon ophthalmological disease manifesting at birth and accounting for 0.01-0.04% of total blindness. Acetozalamide, a carbonic anhydrase inhibitor is one of the options in the medical treatment of glaucoma and acute glaucoma crises. Carbonic anhydrase inhibitors are a class of pharmaceuticals, which are being used as anti-glaucoma and diuretic agent and for their anti-migraine and antiepileptic actions. Carbonic anhydrase inhibitors (topiramate, lacosamide, methazolamide) other than acetozalamide have been associated with psychotic disorders. Psychotic disorder possibly induced by acetazolamide in a male adolescent with blindness due to congenital glaucoma is going to be presented in this case report.
Key words: Acetazolamide, blindness, carbonic anhydrase inhibitors, congenital glaucoma, psychosis
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