Background: Chronic liver disease (CLD) is a progression of disease in the liver for more than 6 months which includes, progressive destruction of liver parenchyma followed by regeneration and fibrosis which leads to cirrhosis. The prevalence rate of CLD was estimated around 1.5 billion worldwide. Among the causes in 2016, cirrhosis holds the 11th place in the order of mortality and 15th place in the order of morbidity worldwide and in 2017, CLD caused death around 1.32 million.
Aims and Objectives: The aim of the study was to assess the drug practice pattern in CLD patients in a tertiary care teaching hospital.
Materials and Methods: A prospective, observational, and cross sectional study was done at SRM Medical College Hospital and Research Centre. A total of 105 CLD patients were included in the study after considering the inclusion and exclusion criteria. Prescriptions were reviewed to know the prescribing indicators and patient indicators.
Results: One hundred and five prescription were reviewed, out of which the most commonly prescribed drugs were, antiulcer drug group 56 (53%), hepatoprotective agents 53 (50%), anti-microbial agents 39 (37%) followed by nutrients supplements 17 (16%), laxatives 13 (12%), and diuretics 10(8.5%).
Conclusion: The most commonly prescribed drugs were antiulcer drug to reduce the gastric secretion, hepatoprotective agents to improve the liver function, and anti-microbial agents to decrease the secondary bacterial infections.
Key words: Chronic Liver Disease; Cirrhosis; Alcoholic Liver Disease; Hepatoprotective Agents; Portal Hypertension; Hepatorenal Syndrome; Hepatic Encephalopathy
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