A large size had or macrocrania (and macrocephaly) is one of the common pediatric neurological conditions that affect up to 5% of the population. An abnormally large head may be due to the true enlargement of the brain (megalencephaly) or may be due to many other underlying conditions i.e. hydrocephalus or cranial thickening. A number of disorders can lead to a large size of head in neonates and children and it is important to identify and recognize even subtle cases, and causes, and diagnose major and easily treatable causes. The purpose of the present article to discuss the etiological and clinical of various disorders causing an abnormally large head that may or may not require surgical intervention.
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