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Original Article



Antioxidant potential of methanol Root extract of Mentha arvensis L. from Kashmir Region

Mubashir Hussain Masoodi, Mohammad Akbar Dar, Adil Farooq Wali, Mudasir Ahmad Mir, Nida Sadiq Shapoo.




Abstract

The study was carried out to evaluate the phytochemical constituents and antioxidant potential of methanol root extract of Mentha arvensis L. from Kashmir region. The antioxidant activity of methanol root extract of Mentha arvensis L was evaluated by using 1, 1-diphenyl, 2-picrylhydrazyl (DPPH) scavenging, reducing power, metal chelating, nitrous oxide scavenging and hydrogen peroxide scavenging assays. It was found that the total phenolic content and total flavonoid content was found to be 9.12 and 32.14 mg/g respectively. The percentage inhibition values of DPPH scavenging for methanol extract were found to be 35.83%. The percentage inhibition values of Nitrous oxide scavenging for extract were found to be 39.11%, the percentage inhibition values of H2O2 scavenging for extract were found to be 21.72%, the percentage inhibition values of metal chelating activity of methanol extract at the concentration of 500 μg/ml was found to be 79.31% and that for standard ascorbic acid was found to be 96% at same concentration and the reducing power of extract was found to be 0.75 at concentration of 0.25mg/ml. The results indicate that the methanol root extract of Mentha arvensis L. has good antioxidant potential and it can be regarded as promising candidates for natural plant sources of antioxidants with high.

Key words: Mentha arvensis; DPPH; reducing power; nitrous oxide; metal chelating; H2O2.






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