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Original Research

BMB. 2023; 8(4): 370-377


Predictors of No-Reflow Phenomenon Development in Patients Presenting with ST-Segment Elevated Myocardial Infarction and Treated with Primary Percutaneous Coronary Intervention

Esra Dönmez, Sevgi Özcan, İrfan Şahin, Ertuğrul Okuyan.




Abstract

Objective
No-reflow phenomenon is known as a complication of percutaneous coronary intervention (PCI). The rate of no-reflow phenomenon was reported between 2-44% differing on the accompanying situations and more frequent in acute myocardial infarction. Predictive factors for no-reflow phenomenon have not been clearly defined. We aimed to define predictive factors for no-reflow development in patients who presented with ST-segment elevation MI (STEMI) and treated with primary (PPCI).
Materials and Method
Patients who underwent PPCI between 2017 and 2021 in our clinic were included retrospectively. Demographic, clinical and laboratory findings were recorded. Two groups generated according to no-reflow development: no-reflow (+) and (-).
Results
Six hundred eighty-nine patients were involved (71.8% male). Mean age was 55,9  8,7 years. 107 patients (15.5%) were formed no-reflow (+) group and 582 patients were formed no-reflow (-) group. Left ventricular ejection fraction, troponin, fasting blood glucose, TIMI thrombus grade and TIMI thrombus category were determined as independent predictors of no-reflow development.
Conclusion
Considering the relationship between no-reflow development and adverse outcomes (in-hospital adverse cardiac events, left ventricular remodeling, malignant ventricular arrhythmia and heart failure), it may help to identify the factors that predict the risk of no-reflow and take preventive measures to improve the long-term outcome.

Key words: No-reflow; TIMI thrombus grade; ST Elevation Myocardial Infarction






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