Abstract

It is now evident that COVID-19 not only affects respiratory system but is a multisystemic disease including skin where lesions have a wide spectrum of presentation. Even though the focus of attention has now changed to vaccines for achieving herd immunity to COVID-19, the detrimental effects of these vaccines must be highlighted because they have a bearing on their widespread acceptance. Moreover, the approved vaccines have not been studied thoroughly, thereby leaving lacunae in its literature. Immunomodulation brought on by the vaccine, particularly T-cell dysregulation that allowed the varicella-zoster virus to escape from the dorsal root ganglia, is likely to cause Herpes-Zoster infection in Covishield-vaccinated immunocompetent people. This study demonstrates such kind of an immunomodulation in two young immunocompetent individuals, which is a rare entity.

Key words: Herpes Zoster; COVID-19; Vaccination