Home|Journals|Articles by Year|Audio Abstracts
 

Original Article



Evaluation and comparison of 15 short tandem repeat loci of south and west Indian population for use in personal identification applications

Prabakaran Mathiyazhagan, Thangaraju Palanimuthu, Agasthi Padmanathan.




Abstract

The objective of this research was to conduct an analysis of the frequency of alleles as well as forensically relevant parameters such as match probability, power of exclusion, polymorphic information content, observed, and expected heterozygosity, homozygosity, paternity index, and discrimination capacity (DC). In all, 209 unrelated people from South Indian groups and 201 people from West Indian populations were examined, and their frequency and statistical attributes were compared. In this research, 15 short tandem repeats (STRs) loci were examined utilizing a multiplex PowerPlex 16 System kit. These loci were CSF1PO, TPOX, D8S1179, TH01, Penta E, D18S51, D21S11, D3S1358, FGA, Vwa, Penta D, D16S539, D7S820, D13S317, and D5S818. With the help of the FORSTAT program, 15 STR frequencies and forensic significance parameters were computed. Within the population, there was no evidence of any departure from the Hardy–Weinberg equilibrium. The maximal allele frequency at TPOX was found to be 0.4976 in the South Indian population, 0.4925 in the West Indian population, and 0.5040 in the combined Indian population, respectively. Similar to the previous statement, the minimum allele frequency was seen at several loci throughout all three investigations. The Penta E and TPOX were found to be the locus with the highest and the lowest degree of polymorphism in the south and combined Indian population, respectively; whereas the locus D18S51 and TPOX recorded the highest and lowest degree of polymorphism in the West Indian population.

Key words: Keywords: Short Tandem Repeat, FORSTAT, Hardy-Weinberg, Indian Population






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.