More than 70% of patients with locally advanced head and neck malignancies (LAHNC), poor performance status, and eligibility for palliative radiation (RT) for symptom relief present in India. In this prospective trial, patients with LAHNC at a local cancer centre in north-west India will be treated with two distinct short-course hypo-fractionated RT regimens. There were 7 females and 33 males in this study. The bulk of our study group consisted of smokers and tobacco chewers, and the majority had this habit for 20–30 years, according to the results. In our study population, there was an overall improvement in quality of life, along with improvements in pain, speech, and overall health. In conclusion, patients' quality of life significantly improved in both groups, and there was no statistically significant difference between the two. The Christie regime may be similarly helpful in treating some patients to obtain a complete response.
Key words: Head Cancer, Neck cancer, hypofractionated palliative radiation therapy
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