Case Report |
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IJMDC. 2023; 7(7): 1054-1057 Unilateral periorbital swelling as initial rare presentation of pediatric leukemiaMerai Alshehri, Omar Kirat, Ali M. Almaely, Yazeed Alshahrani, Abdulmohsen Nasser H. Alshahrani, Abdulmajeed A. Alkhathami, Hezam Shalan H. Alshahrani. Abstract | | | | Background: Acute lymphoblastic leukemia (ALL) is considered the most typical type of cancer in children, representing around 26% of childhood cancer.
Case Presentation: A 13-month-old girl was presented to our clinic who developed unilateral periorbital swelling as her initial sole symptom of ALL. In this report, we described this case with a summary of previously reported cases. The patient previously medically free, was presented with left periorbital swelling and inferior globe displacement, progressing over the preceding 3 weeks. At the initial presentation, slit lamp examination revealed a normal anterior segment with characteristic leukemic retinopathic changes in both eyes with no detected hepatosplenomegaly or enlarged lymph nodes. On investigation, a peripheral smear and bone marrow biopsy showed 80% blast cells. A CT scan showed varying degrees of bilateral extraocular/ocular muscle infiltration. ALL was diagnosed, and the patient immediately underwent induction chemotherapy.
Conclusion: This case highlights the importance of understanding and considering rare, aggressive diseases potentially masquerading as simple periorbital edema.
Key words: Periorbital swelling, children, leukemia
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