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Original Research

BMB. 2022; 7(2): 102-109


COULD ASYMMETRIC DIMETHYLARGININE HAVE A ROLE IN COVID-19?

Müfide Arzu Özkarafakılı, Zeynep Mine Yalçınkaya Kara, Mustafa İlteriş Bardakçı, Işıl Kibar Akıllı.




Abstract

Background
COVID-19 is a disease with respiratory involvement and the virus-induced endothelial dysfunction is pronounced in the center of clinical course. To analyze the laboratory findings and the associations, in COVID-19 patients, may help better understanding the pathophysiology of this disease.
Material Method
We analyzed the laboratory markers including WBC, platelet, MPV, RDW, LDH, procalcitonin, arterial blood gas values and ADMA levels of 83(35 female) hospitalized COVID-19 patients with pneumonia. 30 healthy persons were enrolled as a control group and laboratory findings were compared.
Results
No significant difference of ADMA levels (median value 225.6 μg/L vs 225.6 μg/L) was noted between COVID-19 patients and control group(p=0,771). ADMA had an inverse correlation with RDW (r=-0.391, p

Key words: ADMA, PNEUMONIA, COVID-19






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