Background: Pregnancy-associated complications are not uncommon even in healthy women. Among high-risk pregnancy is the presence of anemia including sickle cell disease (SCD). The present study aimed at evaluating the pregnancy outcome among SCD pregnant women in a hospital in Al-hasa.
Methodology: Fifty-nine SCD pregnant women who attended the maternity hospital from the period of January 2014 to March 2016 have been included in the study. The effect of the guidelines of management of SCD pregnant women was studied and compared to the following factors: fetal outcome, mode of delivery, Apgar score, birth weight, still birth, admission intensive care unit (ICU), history of pre-eclampsia/eclampsia (PET), history of deep venous thrombosis (DVT), fetal surveillance, and Gestational Age (GA) at time of delivery.
Results: The present study has uncovered that there is an increased risk of pregnancy-related complications among SCD pregnant women. The results showed that there is an increase in the morbidity and mortality among the offspring of mothers with SCD in Al-hasa. Fetal outcome, Apgar score, birth weight, still birth, admission to ICU, history of PET, history of DVT, and GA at time of delivery were found to have a p-value of 0.0001, which means that there is a significant relationship between these variables and pregnancy-related complications.
Conclusion: In conclusion, Saudi women with SCD in Al-hasa are at a great risk of having pregnancy and birth complications. The issue must be approached by facilitating the right care and well-educated staff, especially about SCD, which is prevalent in the eastern region of Saudi Arabia.
Key words: Sickle cell disease (SCD), Intrauterine growth restriction (IUGR), Intrauterine fetal death (IUFD), Pre-Eclampsia/eclampsia (PET), Deep Venous Thrombosis (DVT)
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