Acquired immunodeficiency disease syndrome (AIDS) and AIDS-related illnesses continue to cause a public and economic burden on any given community. Different preventive strategies have been reported, which vary in their effectiveness and safety to limit human immunodeficiency virus (HIV) transmission, the causative virus of AIDS. Antiretroviral therapy (ART) is the main agent used for HIV treatment, and it has been used as a prevention method, or prophylaxis, to prevent HIV transmission. This review was conducted to evaluate clinical trials, and updated recommendations for preventing HIV infection for individuals at risk using ART. We reviewed the literature, and six studies responded to our inclusion criteria. Most of the recent studies that used ART seemed effective in preventing HIV infection among seronegative individuals. Further studies on a larger and different population are recommended to ensure the best preventive methods against HIV.
Key words: HIV, AIDS, PREP, France, Europe, WHO
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