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A study on correlation between Vitamin D and glycated hemoglobin in Type 2 diabetes mellitus patients attending a tertiary care hospital in West Bengal

Vikash Raj, Shashank Kanchan, Richa.

Abstract
Background: Vitamin D is a steroid hormone, responsible for calcium homeostasis. It has shown to affect insulin synthesis, secretion, and action. Diabetes is a non-communicable systemic disease caused by multiple factors cumulatively leading to insulin deficiency and insulin resistance. In this context, there was a research question to know the extent of association between Vitamin D levels and Type 2 diabetes mellitus.

Aim and Objective: The study aims to establish an association between Vitamin D levels and glycosylated hemoglobin (HbA1c) levels in Type 2 diabetes mellitus patients.

Materials and Methods: It was a hospital-based retrospective study done over a period of 3 months at a tertiary care center of West Bengal. The values of fasting blood sugar (FBS), postprandial blood sugar, HbA1c, and Vitamin D level were recorded. Statistical analysis of the data collected was done using SPSS ver. 20.

Results: Out of a total of 148 patients, 74.3% had deficiency, 21.6% insufficiency, and 4.1% had normal levels of Vitamin D. Similarly, 83.1% of the patients had HbA1c level more than and equal to 6.5% and 16.9% had HbA1c levels less than 6.5%. A negative correlation between Vitamin D and FBS levels and HbA1c and Vitamin D was seen.

Conclusion: There is a definite inverse correlation between Vitamin D and HbA1c levels.

Key words: Fasting Blood Sugar; Glycosylated Hemoglobin; Postprandial Blood Sugar; Vitamin D



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