The objective of the study was to compare the phytochemical investigation and anti-inflammatory activity of ethanolic extract of two variety of shankhpushpi i.e. Convolvulus pluricaulis Choisy and Evolvulus alsinoides Linn. The phytochemical analysis was performed followed by characterization with FTIR and NMR spectroscopy and total phenolic content determination. Anti-inflammatory activity was evaluated by two i vitro models i.e. heat induced and hypotonic solution-induced hemolysis. Total phenolic content of C. pluricaulis and E. alsinoides was 668.143 + 1.107 and 593.453 + 0.565 micro g GAE/ml extract respectively. In heat hemolysis, inflammation was significantly reduced at 50, 100 and 300 micro g/ml in CP and at 50, 100 and 200 micro g/ml in EA. Both extracts were effective in inhibition of hemolysis and results of
both were compared than CP shows better results than EA.
Key words: Inflammation; hemolysis; extraction; phenolic content; Shankhpushpi
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