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Clinicopathological features of very young Balinese women with breast cancer: A Cancer Registry data from 2016-2021

Citra Aryanti,Putu Anda Tusta Adiputra,I Wayan Sudarsa.




Abstract
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Introduction Breast cancer in very young women showed varied clinicopathological data among studies. This study presented the clinicopathological features of very young Balinese women with breast cancer from Cancer Registry in 2016-2021
Methods This study retrospectively studied the characteristic of Balinese women with breast cancer aged less than 35 years old that has been histopathology confirmed. The clinico-pathology parameters included were age of menarche, parity, education, employment, family history, location and area of breast lump, histologic subtypes, grade, lymphovascular invasion, tumor infiltrating lymphocytes, and AJCC TNM-based breast cancer’s stage was recorded. Statistical analysis was performed using the SPSS 16.0 software.
Results There were 100 Balinese women under 35 years of age (5.16% of the total population of women with breast cancer from 2016-2021) diagnosed to have breast cancer in Bali from January 2016 to October 2021. Majority subjects had age of menarche of 12-14 years old (66%), multiparity (56%), highest education of senior high school (50%), housewife (40%), no family history of breast cancer (92%), presented in advanced stage (68%), mostly in stage IIIB (26%),had histology type of non special type of invasive carcinoma (81%), histological grade II (48%), no presence of lymphovascular invasion (33%), positive tumor infiltrating lymphocytes (67%), and with luminal B (47%) subtype.
Conclusions The clinopathological features of very young female subjects with breast cancer in Bali were quite similar to others studies and the general population of breast cancer subjects.

Key words: very young, breast cancer, clinicopathology






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