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Original Research

TAF Prev Med Bull. 2010; 9(4): 297-302


Antiinfammatory Effects of Pyrenacanthia Staudtii Engl. (Icacinaceae) Aqueous Leaf Extract in Rodents

Emmanuel,Olorunju,Awe, Modupe,Janet,Makinde, Kamoru,Olayemi,Wakeel1, Simeon,Olatunde,Kolawole.




Abstract

AIM: The continued search for potential and safe anti-inflammatory agents is important, in view of the roles played by proinflammatory factors in diseases such as asthma, rheumatoid arthritis, cancer and neurodegerative disorders. The Nigerian flora is rich in medicinal plants which are employed in traditional folk medicine for various inflammatory disorders. We therefore evaluate the antiinflammatory activity of the aqueous extract of the leaves of.
METHOD: The antiinflammatory activity was evaluated using egg albumin, agar-induced paw edema models for acute inflammation, complete Freud Adjuvant (CFA)-induced arthritis and cotton pellets granuloma models for chronic inflammation in rats.
RESULTS: PSE, produced significant (P

Key words: Pyrenacanthia Staudtii, Aqueous Extract, Anti-İnflammatory Activity

Article Language: Turkish English






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