Abstract

Background: Dengue fever has been an important public health problem in recent years. Hepatic involvement in Dengue ranges from elevated liver enzymes to fulminant hepatic failure. The present study was carried out to evaluate liver dysfunction in patients with dengue infections and the correlation between liver function tests and platelet count.
Methods: Hospital-based case-control study was conducted on 141 hospitalized with Dengue infection (NS 1 and IgM positive). Dengue Seropositive patients were selected and subjected to complete blood count, and Liver function tests were analysed.
Results: The participants were found to have elevated SGOT, SGPT and lower serum albumin and platelet count levels compared to the control on evaluation. A significant negative correlation was noted between SGOT/ SGPT levels and baseline platelet counts. The Pearson correlation between platelet count and SGOT showed r = -0.185 and p-value

Key words: SGOT, SGPT, Dengue