AIM: This study objected to determination of distribution of bacterial agents, resistance proportions in community-acquired urinary tract infection (UTI) in center of Mersin province and objected to regional treatment guide towards to our evidence.
MATERİAL AND METHOD: In this study, included patients of pre-diagnosed as UTI based on clinical and laboratory in 11 health care centers between 11/01/2008–07/01/2009. Health care centers were checked for as daily and delivered appropriate urine samples for this study which collected sterile urine collection bottles. Urine samples were cultured including ≥leukocyte/mm3 with thoma slides, as a result of culture, samples of being on one type bacterial growth and ≥105 cfu/mL have done statically analysis.
RESULTS: Totally 480 samples were collected and 311 (64.8%) of them evaluated to as statistic significant. In bacterial culture analysis, E. coli (80.7%) was the most commonly identified and as descending order found to Klepsiella spp. (8.7%), CNS (7.8%), Proteus spp. (1.9%), Enterobacter spp. (0.6%), and Pseudomonas spp. (0.3%). ESBL was determined to 10.0% of E. coli isolates, 3.7% of Klepsiella spp. isolates and also IBL was determined in two Enterobacter spp. isolates. Oxacillin resistance in CNS isolates was found as 12.5%. Imipenem resistance in Gram negative uropatogens was not detected and resistant rates were detected; 0.3% in amikacin, 0.7% in cefoperazone/sulbactam, 2.8% in cefoxitin, 6.3% in nitrofurantoin, 10.8% in ceftriaxone, 16.7% in ciprofloxacin, 16.7% in cefuroxime, 42.2% in cotrimoxazole, 97.6 % in amoxicillin clavulanic acid, and 94.4% in ampicillin sulbactam. There were no detected to resistance to glycopeptides and linezolid in gram positive agents.
CONCLUSION: Ampicillin, ampicillin sulbactam, amoxicillin clavulanic acid, and cotrimoxazole antibiotics were out of the being preference for reason of resistance rates in UTI empirical treatment in our region.
Key words: Antimicrobial Agents, ESBL, Urinary Tract Infection Article Language: Turkish English
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