Members of the genus Streptomyces are of great importance for biotechnology due to their ability to produce a large array of natural products, including antibiotics, anticancer agents and immunosuppressants. Recent research has increased our knowledge and understanding of the antimicrobial effect of mangrove Streptomyces. In a systematic screening effect, Streptomyces isolates from different mangrove forest were investigated for antimicrobial activity against bacterial pathogens and potentially active secondary metabolites. The different solvent extracts (Butanol, Ethyl acetate,ethanol, hexane) of selected isolates were screened for their antimicrobial activity by well cut method. The Zone of inhibition was measured in all extracts revealed a wide range of antimicrobial activity against pathogenic bacteria. The overall results of the antimicrobial activity indicates the presence of the antibiotics in Streptomycetes sp from mangrove forest evidenced by the presence of the compounds that can active against bacterial pathogens.
Key words: Mangrove, Streptomyces, Compounds, Antibiotics, Bacteria.
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