Breast cancer is one of the major burdens that affect women and their life. Many studies showed that many chemopreventive agents have anticancer effect; however, some studies were contrary to them. This article reviewed and summarized the available medical evidences of chemoprevention in breast cancer. An extensive literature search was carried out in the following databases including: Medline (PubMed interface), Scopus, and Google Scholar to identify articles that discussed the role of chemoprevention in breast cancer. The following keywords were used independently and in combination including carcinogenesis, breast cancer, and chemoprevention in the search process. The retrieved articles were further explored in order to find other relevant resources. Although various chemopreventive agents have been investigated in breast cancer and there have been major achievements in this field, more research work and clinical trials are needed to determine the therapeutic efficiencies of these agents in human being.
Key words: Chemoprevention, breast cancer, carcinogenesis.
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