Background: Thyroid hormone has very strong effects on the central nervous system and causes central craniopathy in hypothyroid patients.
Aim and objectives: The study was aimed to assess the central craniopathy in hypothyroidism and compare central craniopathy in hypothyroid patients and euthyroid subjects.
Materials and Methods: The study population comprised of 50 hypothyroid patients and 50 euthyroid subjects aged above 20 years. Subjects with a history of demyelinating disorders, head injury, or facial pain were excluded from the study. Blink reflex (BR) latencies were recorded bilaterally using RMS EMG MKII machine.
Results: On comparing the mean of the test between euthyroid and hypothyroid patients, BR latencies were delayed in hypothyroid patients.
Conclusion: There is an increased prevalence of central craniopathy in hypothyroidism in comparison to the controls.
Key words: Blink Reflex; Central Craniopathy, Demyelinating Diseases, Hypothyroidism