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Evaluation of the relationship between COVID-19 and hyperglycemia

Seval Muzeyyen Ecin, Deniz Gezer.




Abstract

The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enters cells via the angiotensin-converting enzyme. This enzyme is found in many organs, including the pancreas. Thus, the virus enters the pancreatic islets via this enzyme and causes acute hyperglycemia by triggering acute beta-cell dysfunction. Hyperglycemia is an independent risk factor that increases the mortality and morbidity of COVID-19. Therefore, we aimed to evaluate the presence of elevated glucose levels and/or DM in COVID-19 patients and their relationship with clinical findings, biochemical and inflammatory markers, and prognosis of COVID-19. The study included 300 patients. Advanced age (OR: 1.0, 95% CI: 1.0-1.1, p: 0.03) and mutant strain (OR:0.1, 95% CI: 0.1-0.3, p:

Key words: COVID-19, hyperglycemia, Diabetes Mellitus.






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