Background. The term dyspepsia comes from a Greek word and represents a disorder which affects the process of digestion. There are 3 specific entities that denote dyspepsia (uninvestigated, functional, and organic dyspepsia). According to ROMA IV criteria, functional dyspepsia (FD) is defined by the presence of symptoms in the epigastric region such as epigastric pain, fullness, nausea, emesis belching discomfort. Functional dyspepsia may be associated with other pathological processes. There are studies that indicate a positive correlation of FP with pathological obesity but very few studies describe an association with visceral obesity. Furthermore, the association of FP and IR has not yet been studied. Objective. The aim of the study was to point out the association between FD, visceral adiposity, and insulin resistance (IR) through a case report. Another goal is to show that IR treatment can positively affect the treatment process of FP. Methods and Case study. In the family medicine clinic, we monitored signs of functional dyspepsia in adipose patients. Tests for insulin resistance (HOMA 1, 2, OGTT and insulinemia), anthropometric measurement and bioelectrical impedance were performed simultaneously, with special reference to the amount of mesenteric adipose tissue. One typical case shows a clear link between functional dyspepsia, increased visceral adipose tissue, and IR. Results and Discussion. In the treated patient, an association between the occurrence of functional dyspepsia, the amount of visceral adipose tissue and IR has been demonstrated. By applying the proposed measures of diet and physical activity, all subjective problems of FP disappeared and the test for insulin resistance was normalized (HOMA 2). Conclusion. This case confirms the existence of a positive correlation between the intensity of FP problems, the amount of visceral adipose tissue and IR. Appropriate recommendations for the treatment of IR can alleviate all the symptoms of FP. They can be applied in primary care practice.
Key words: Functional dyspepsia, Insulin resistance, visceral adipose tissue
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