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Effects of sugammadex on platelet levels and platelet-to-lymphocyte ratio in morbidly obese patients undergoing sleeve gastrectomy

Ozkan Gorgulu, Mehmet Nuri Kosar.




Abstract

Sugammadex is known to have minimal effects on coagulopathy. The aim of this study was to analyse the changes in platelet levels and platelet-to-lymphocyte ratio (PLR) in preoperative and postoperative periods in morbidly obese patients. This retrospective study included a total of 86 morbidly obese patients with a Body Mass Index (BMI) of >40 kg/m2 and with an American Society of Anaesthesiologists Classification score (ASA) III undergoing elective laparoscopic sleeve gastrectomy (LSG). Patient data were obtained from patient files and electronic health records system (SARUS). The patients were allocated into two groups namely sugammadex (Group S) and neostigmine (Group N). Preoperative and postoperative (12th hour) hemogram recordings of the patients were examined. Compared to preoperative levels, there was a significant decrease in the postoperative platelet and lymphocyte values of patients in Group S (p

Key words: Sugammadex; platelet count; lymphocyte count; platelet-to-lymphocyte ratio; blood coagulation disorders






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