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Original Article

NOFOR. 2022; 1(1): 1-5


Diagnostic value of serum pentraxin-3 in deep vein thrombosis disease

Yasin Erol, Ali Aygun, Selim Demir, Ahmet Mentese, Umit Mentese, Abdulkadir Gunduz.




Abstract

Aim: We investigated the diagnostic value of Pentraxin 3 (PTX-3), a marker that increases in vascular and inflammatory pathologies, in patients admitted to hospital with deep vein thrombosis clinic.
Materials and Methods: 44 patients admitted to the a tertiary medical faculty hospital and a tertiary training and research hospital, with suspect of deep vein thrombosis included in our study. Patients confirmed to have DVT by doppler ultrasonography named as DVT(+) group, and patients not confirmed to have DVT by doppler ultrasonography named as DVT (-). PTX-3 levels determined in blood samples and compared between these groups.
Results: Median levels of D-dimer in DVT(+) group was 3.92 μg/ml (1.57- 6.05), and in DVT (-) group was 1.47 μg/ml (0.97-2.37), and a statistically significant difference was found between these groups (p

Key words: Deep vein thrombosis (DVT), D-dimer, Diagnosis, Pentraxin 3 (PTX-3)






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