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Original Research

RMJ. 2019; 44(2): 418-420


Comparing neutrophil gelatinase associated lipocalin with creatinine to detect renal injury PCI

Amna Ihsan, Nasim Ilyas, Fouzia Hanif, Farhana Ayub, Usman Nawaz, Kashif Rahim.




Abstract

Objective: To compare new biomarker neutrophil gelatinase associated lipocalin (NGAL) with currently used creatinine (SCr) in early detection of renal injury resulting as adverse effect of contrast angiography.
Methodology: We recruited 151 subject of planed Percutaneous Coronary Intervention (PCI). Blood samples were drawn before and serially for 5 days of the PCI and biochemical analysis were done immediately.
Results: Pre and post PCI, serum NGAL levels were markedly different, showing increase of 61 µg/L. The serum creatinine also showed increase after two days.
Conclusion: This study was suggestive of high and rapid predictive value of NGAL in case of acute renal damage post PCI.

Key words: Acute renal damage, serum neutrophil gelatinase associated lipocalin, contrast induced nephropathy.






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