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Population-genetic Aspects of Breast Cancers and Association with Rh Factor in Selected SampleAzra Metovic, Jasmin Musanovic, Nerman Ramic, Orhan Lepara, Damir Secic, Esad Pepic, Svjetlana Loga Zec, Senad Sljuka. Abstract | | | | Background: Breast cancer in women is the second most common and accounts for approximately 18% of all malignant tumors in women worldwide. The etiology of breast cancer is not clear enough. Starting from the assumption that the manifestation of breast cancer may have a multifactorial model, this article compares the population-genetic structure of patients (experimental group) with the population-genetic structure of healthy population (control group). Objective: The aim of the study was to examine the possible genetic basis of the Rh factor relationship with selected homozygous-recessive traits of females with breast cancer, and to diagnose the probability (assess the risk) of developing the disease in healthy women by analyzing homozygous-recessive traits (HRT). Methods: This are an anthroposcopic-qualitative study that included two groups of subjects, experimental and control (a total of 80 subjects). An analysis of the percentages within each group was performed using the Chi-square test. The results are presented in tables, and the accepted level of significance is at the level of p
Key words: breast cancer, recessive trait, homozygous recessive, Rh factors.
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