The aim of this study is to assess the effects of high blood glucose levels in male rats with diabetes induced by alloxan on their physiological conditions. Diabetes mellitus is a category of metabolic hyperglycemia disorders caused by insufficient body production or pancreatic action. In addition to hyperglycemia, a number of other factors are also important for pathogenesis, such as Hyperlipidemics and cortisol oxidative. Forty-five mature male rats were used in this study, these were divided into 3 groups, Control group(G1) : gavage distilled water, Group2(G2): injection intraperitoneally with Alloxan150 mg/kg bw for two weeks, and Group3(G3): injection intraperitoneally with Alloxan 150mg/kg bw for twenty-four days. Blood samples taken from all groups estimation of Peroxynitrite, GSH, CAT, and SOD concentrations%. The findings revealed a significant improvement in diabetic classes in glucose (p
Key words: Rats, Diabetes, Physiological parameters, SOD, GSH and CAT
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