Disseminated peritoneal leiomyomatosis is a benign disease with unknown etiology and an indolent course. The site of origin can be mesentery, omentum, or peritoneum. Diagnosis is challenging and more often lead to misdiagnosis. It can be managed both surgically or by nonsurgical options. The nonsurgical modalities include limiting hormonal exposure which has shown to decrease tumor size. Avoiding Oral contraceptive pills (OCP) and hormonal replacement therapy (HRT), and giving the patient gonadotrophin-releasing hormone agonist and aromatase inhibitor therapy have been found effective. However, there are no firm guidelines in the literature regarding the management of this condition. If left untreated, it can cause complications such as pain, bleeding, chronic constipation, and infertility. Prognosis is good but recurrence is possible after tumor resection. There is little evidence regarding the follow up of this condition.
Key words: Disseminated peritoneal leiomyomatosis, adenexal mass, surgery, lower middle income country
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