Neurosyphilis is an infection of central nervous system caused by Treponema pallidum and may present with neuropsychiatric symptoms. Neurosyphilis can mimic virtually any psychiatric disorder, including depression, mania, psychosis, personality changes, delirium and dementia. Neurosyphilis is a mysterious disease because it imitates psychiatric diseases leading difficulties in differential diagnosis. In addition, antibiotics may change its natural course, and therefore, its clinical manifestations. Mild or various forms of neurosyphillis may present, instead of the conventional form. In this paper, a case who could not have been detected at primary or secondary stages and presented with neuropsychological symptoms (tertiary neurosyphilis) was discussed.
Key words: Neurosyphilis, psychiatric symptoms, dementia
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