Aim: This study assessed the prevalence of WT in Africa and Asia as it relates to smoking index and malignant tumors of the parotid gland.
Materials and Methods: Peer-reviewed articles found on Google Scholar, Scopus, EMBASE, Web of Science, and PubMed Central were systematically reviewed.
Results: Significant higher prevalence of WT and smoking index (intensity and prevalence of smoking) were observed in Asia than in Africa (p= 0.003 and p=0.001, respectively). A significant direct relationship was observed between the frequency of WT and smoking index (p= 0.001) while a significant inverse relationship between the prevalence of WT and malignant tumors of the parotid gland (p= 0.039) was also observed. In Africa, South Africa and Morocco had the highest prevalence of WT (13.4% and 11.5%, respectively) while Tanzania and Nigeria had the lowest prevalence of WT (3.6% and 0.0%, respectively). In Asia, Taiwan and South Korea had the highest prevalence of WT (46.6% and 38.8%, respectively) while Iran and Pakistan had the lowest prevalence of WT (7.6% and 3.5%, respectively).
Conclusion: This review revealed that the high prevalence of WT in Asia could be due to a high smoking index in the continent. It suggests that the incidence of WT could be used as an alternative tool for monitoring the effect of smoking across countries.
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