Background: Pregnant mothers with babies diagnosed to have Beckwith-Wiedemann syndromes (BWSs) have been reported in very few case reports in the literature.
Case Presentation: This case report describes the course of two pregnancies in a woman with BWS. The main metabolic issues encountered were recurrent episodes of hypoglycemia and suspected diabetes insipidus in pregnancy. Labor and delivery were uneventful, but she had significant secondary postpartum hemorrhage on both occasions.
Conclusion: This syndrome has not been studied in the antenatal period and its course in pregnancy is not well known. We discuss possible complications that women with this syndrome could present with, the need for blood glucose and urine monitoring, a multidisciplinary approach, and close liaison with medical colleagues to identify and treat metabolic complications early.
Key words: Beckwith-Wiedemann, pregnancy, complications, case report
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