Menopause is a physiological process denoted as Rajonivrutti (Cessation of menstruation) in ayurveda. When it causes discomfort either to mind or body, attains a disease state requiring medical interference. Psychological variations are a major concern during menopausal transition. Approximately 80% of women suffer from psychological symptoms during this period. Lashuna (Garlic) helps to uphold psychological health through vata-kaphahara (pacifying vata-kapha humors), medhya (Nootropic) and rasayana (Rejuvenation) property as well as its action on neurotransmitters. 30 women between the age group 45 to 55 years undergoing menopausal transition were screened using Menopause rating scale. Selected women were administered with Lashuna capsule containing 500 mg of aqueous extract of garlic. Outcome was assessed after thirty days of treatment and 15 days of follow up. At the end of 30 days of intervention, subjects reported a significant reduction in psychological symptoms such as irritability, anxiety, depression, and sleep problem (P< 0.05).The results indicate that vata kaphahara (pacifying vata-kapha humors), nootropic (medhya), rejuvenating (rasayana) property along with clearing the bodily channels (srotoshodhana), garlic may help in reducing psychological complaints of Menopausal transition. Moreover nootropic, antidepressant, anxiolytic and adaptogenic activities of Allium sativum has been proven by several research. This permits larger clinical trials to validate the findings of this pilot study.
Key words: Anti-depressant; Anxiolytic; Lashuna capsule; Menopausal transition; Nootropic
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