Introduction:
Mucosal melanoma is a subtype of Malignant Melanoma (MM). Urethral malignant melanoma is an extremely rare entity with a poor prognosis. It is associated with early recurrence and metastases.
Methodology:
It is a retrospective case report. Data were retrieved from the Human Information System (HIS), an electronic data-based system of Shaukat Khanum Memorial Cancer Hospital and Research Centre.
Case Discussion:
We presented a case of MM of the urethra. Forty-year-old male presented with hematuria and mass in the penile urethra for 6 months. Cystoscopy and excision of the mass were performed which showed malignant melanoma. After complete pre-operative workup and multi-disciplinary team meeting, anterior urethrectomy and suprapubic cystostomy were performed. Adjuvant interferon was given. However, the patient presented with bilateral inguinal lymph node metastases which were detected on a Positron Emission Tomography scan. He was offered radical treatment. He did not consent to the surgery. The patient died after 1 year of completion of treatment.
Conclusion:
With little knowledge reported, the management of urethral MM is still controversial. Proper planning and the aggressive nature of treatment might help in curative management.
Key words: Malignant Melanoma, Mucosal Malignant Melanoma, Genitourinary Malignant Melanoma, Rare Urethral Cancer, Malignant Melanoma of Urethra
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