Abstract

Aim: Ileocecal syndrome also called typhilite; It is defined as inflammation of the cecum and surrounding tissues seen in immunosuppressed patients. Typhilite is a serious disease in the ileum, cecum, and ascending colon with segmental inflammation and necrosis due to ulceration. The disease has difficulties in its diagnosis, treatment, and surgery. We aimed to examine the difficulties in diagnosis and treatment in this disease, which has high morbidity and mortality.
Materials and Methods: Patients who have hematological or solid organ malignancies, diagnosed with neutropenic enterocolitis between January 2014 and December 2019 were included in the study. The demographic information, malignancies, chemotherapy treatments, follow-ups, clinical symptoms, laboratory, and radiology findings of the patients were examined.
Results: A total of 7 patients were identified between the dates indicated, 4 were male and 3 were female. The mean age was 58.5. Six of these patients had hematological and one had solid organ malignancy. All patients had the typical fever (above 38), non-migratory abdominal pain localized to the right lower quadrant, and neutropenia (

Key words: Chemotherapy; ileocecal syndrome; neutropenia; neutropenic enterocolitis; surgery; typhilite