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Original Article



The effect of diagnostic value of biochemical parameters on mortality in COVID-19 patients

Bagnu Orhan, Levent Deniz, Zuhal Aydan Saglam, Gulhan Eren, Berrin Bercik Inal.




Abstract

The present study aims to investigate the effect of the predictive value of Neutrophil to Lymphocyte Ratio (NLR) and several routine laboratory tests on mortality in patients with positive Coronavirus disease-2019 (COVID-19) tests who were treated at Istanbul Training and Research Hospital. Routine laboratory data of patients with positive COVID-19 Real Time-Polymerase Chain Reaction (RT-PCR) results were obtained via the hospital information system. The laboratory tests included ferritin, C-reactive protein (CRP), lactate dehydroge­nase (LDH), aspartate transaminase, creatinine, urea, D-dimer, neutrophil, and lymphocyte count. The number of patients was 2774 and they were admitted to Istanbul Training and Research Hospital between March 10 and June 10, 2020. The statistical data were obtained using SPSS 17.0 version. The patients were divided into two groups, one for mortality (n= 74 patients) and the other for non-mortality (N=2700 patients). In both mortality and non-mortality groups, the ratio of males was higher than females and the difference was not significant (p>0.05). 87.8% of those who lost their lives were treated in the intensive care unit (p

Key words: COVID-19, biochemical tests, hemogram parameters, immunochemical method, mortality






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