Thalassemia trait (TT)-related anemia is a common hematologic problem in Mediterranean region. This type of anemia may be frequently confused with iron deficiency anemia (IDA). Anemia becomes more severe in case of co-existence of both anemia types. This study was carried out with the aim of investigation of iron, folic acid and vitamin B12 levels in patients who were diagnosed with beta thalassemia minor. A total of 183 patients (47 male, 136 female) who were diagnosed with beta thalassemia minor with high performance liquid chromatography (HPLC) method were enrolled in the study. Iron deficiency was detected in 17.52% of women and in 1.6% of men. Decreased vitamin B12 and folic acid values were detected as 28.7% and 10.3%, respectively. As the result of the study, it was concluded that serum iron and vitamin B12 levels should also be measured in assessment of TT patients due to its high prevalence in Mediterranean region. In addition, folic acid is recommended as folic acid deficiency may develop in some patients.
Beta thalassemia minor, iron deficiency anemia, vitamin B12, folic acid
Article Language: Turkish English Similar Articles
Jasmonate- and abscisic acid-activated AaGSW1-AaTCP15/AaORA transcriptional cascade promotes artemisinin biosynthesis in Artemisia annua.
Ma YN, Xu DB, Yan X, Wu ZK, Kayani SI, Shen Q, Fu XQ, Xie LH, Hao XL, Hassani D, Li L, Liu H, Pan QF, Lv ZY, Liu P, Sun XF, Tang KX
Plant biotechnology journal. 2021; ():
Foliar nutrient-allocation patterns in Banksia attenuata and Banksia sessilis differing in growth rate and adaptation to low-phosphorus habitats.
Han Z, Shi J, Pang J, Yan L, Finnegan PM, Lambers H
Annals of botany. 2021; ():
Effect of ultra-high pressure treatment on the functional properties of poly (lactic acid)/ZnO nanocomposite food packaging film.
Cui R, Fan C, Dong X, Fang K, Li L, Qin Y
Journal of the science of food and agriculture. 2021; ():
Performance of reduced fat-reduced salt fermented sausage with added microcrystalline cellulose, resistant starch and oat fiber using the simplex design.
Santos JMD, IgnĂˇcio EO, Bis-Souza CV, Silva-Barretto ACD
Meat science. 2021; 175(): 108433
Reduction of alkalinity supplementation for acid-based wastewater treatment using a thermophilic multi-feed upflow anaerobic sludge blanket reactor.
Omine T, Kuroda K, Hatamoto M, Yamaguchi T, Yamauchi M, Yamada M
Environmental technology. 2021; 42(1): 32-42
Analytical evaluation of serum non-transferrin-bound iron and its relationships with oxidative stress and cardiac load in the general population.
Sugiura T, Dohi Y, Takase H, Fujii S, Seo Y, Ohte N
Medicine. 2021; 100(7): e24722
Severe toxicity of capecitabine in a patient with DPD deficiency after a safe FEC-100 experience: why we should test DPD deficiency in all patients before high-dose fluoropyrimidines.
Maillard M, Eche-Gass A, Ung M, Brice A, Marsili S, Montastruc M, Puisset F, Thomas F
Cancer chemotherapy and pharmacology. 2021; ():
Fat mass and obesity-associated protein regulates lipogenesis via m A modification in fatty acid synthase mRNA.
Sun D, Zhao T, Zhang Q, Wu M, Zhang Z
Cell biology international. 2021; 45(2): 334-344