Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Review Article

SRP. 2013; 4(1): 20-25


Smart Drug Delivery Systems as Game Changers in Therapeutics

Amita Bhandari, Anantha N. Naik, Shaila Lewis.

Abstract
Smart Drug Delivery Systems (SDDS) have emerged as panacea for many clinically useful drugs
weighed down with toxicity. The discovery of Amphotericin B as a liposome has raised hopes
and directed mammoth efforts in SDDS. The concept of manipulation of toxicity has given rise
to additional significant approaches like targeting and use of physico-chemical approaches.
Currently the spectrum of SDDS comprises of targeting liposomes, drug loaded biodegradable
microspheres, stimuli responsive drug polymer conjugates, smart hydrogels, polymeric micellar
particles, intelligent lipoprotein carriers, and nano carriers. There is a wealth of knowledge
accumulated worldwide in the area of SDDS, which can be extremely beneficial to industry as
well as practitioners of health care. In this article an overview of developments are reviewed.

Key words: Liposomes, smart drug delivery systems, stimuli responsive



Similar Articles

Multiple Topoisomerase I (TopoI), Topoisomerase II (TopoII) and Tyrosyl-DNA Phosphodiesterase (TDP) inhibitors in the development of anticancer drugs.
Baglini E, Salerno S, Barresi E, Robello M, Da Settimo F, Taliani S, Marini AM
European journal of pharmaceutical sciences : official journal of the European Federation for Pharm. 2021; 156(): 105594

Balancing Positive and Negative Selection: Evolution of Candida lusitaniae .
Demers EG, Stajich JE, Ashare A, Occhipinti P, Hogan DA
mBio. 2021; 12(2):

Gamma-Secretase Inhibitor (DAPT), a potential therapeutic target drug, caused neurotoxicity in planarian regeneration by inhibiting Notch signaling pathway.
Dong Z, Huo J, Liang A, Chen J, Chen G, Liu D
The Science of the total environment. 2021; 781(): 146735

Efavirenz-loaded polymeric nanocapsules: Formulation, development, and validation of an RP-UHPLC-DAD method for drug quantification, determination of encapsulation efficiency, stability study, and dissolution profile
Amanda Martinez Lyra, Juliana Parente Menezes Ribeiro, Jessica Mendes Nadal, Sinvaldo Baglie, Traudi Klein, Andressa Novatski, Paulo Vitor Farago
Journal of Applied Pharmaceutical Science. 2021; 11(2): 93-101

Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer.
Hang Y, Tang S, Tang W, Větvička D, Zhang C, Xie Y, Yu F, Yu A, Sil D, Li J, Singh RK, Oupický D
Journal of controlled release : official journal of the Controlled Release Society. 2021; ():

Applications of chitosan and chitosan based metallic nanoparticles in agrosciences-A review.
Chouhan D, Mandal P
International journal of biological macromolecules. 2021; 166(): 1554-1569

Policy Action Within Urban African Food Systems to Promote Healthy Food Consumption: A Realist Synthesis in Ghana and Kenya.
Booth A, Barnes A, Laar A, Akparibo R, Graham F, Bash K, Asiki G, Holdsworth M
International journal of health policy and management. 2021; ():

Synthesis and characterization of a PAMAM dendrimer nanocarrier functionalized by HA for targeted gene delivery systems and evaluation .
Hu H, Wang H, Liang S, Li X, Wang D
Journal of biomaterials science. Polymer edition. 2021; 32(2): 205-228


Full-text options






Advertisement
American Journal of Diagnostic Imaging

SUBMIT YOUR ARTICLE NOW




ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.