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Original Article

pnr. 2011; 2(2): 55-57


Lack of antiglycation activity of fresh juice of whole plant of Enicostema axillare (Lam.) Raynal

WD Ratnasooriya, K.I.W.K Somarathna, G.A.S Premakumara, E.R.H.S.S Ediriweera.


Abstract

Objective: To investigate the antiglycation potential of fresh juice of whole plant of Enicostema axillare (Lam.) Raynal. in vitro. Materials and Methods: Antiglycation activity of fresh juice of whole plant was determined in vitro using five concentrations (25, 50, 100, 200, and 400 μg/ml) by determining their ability to inhibit the formation of advanced glycation endproducts in a bovine serum albumin / glucose system using fluorescence spectroscopy. Results: There is no antiglycation activity in vitro of fresh juice of E. axillare plant. Conclusion: It is unlikely that impairment of diabetic complications by E. axillare whole plant juice as claimed by ayurvedic and traditional physicians is mediated via antiglycation activity.

Key words: Antiglycation activity, diabetic complications, Enicostema axillare, Enicostema littorale






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