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Original Article

. 2019; 10(2): 58-64


The Metabolic Syndrome (MetS) Does not Confer Additional Risk Above and Beyond its Individual Components for Left Ventricular Remodeling

Rosaley Prakaschandra, Datshanna Prakesh Naidoo.

Abstract
Introduction: The detection of preclinical changes in Left Ventricular (LV) structure in the Metabolic Syndrome
(MetS) has not been adequately studied, although MetS is strongly associated with increased cardiovascular risk.
The influence of the MetS and its individual components on LV geometry across age groups in a cohort of SA Indians
was studied. Method: Data on 902 randomly selected participants, a sub-group of the Phoenix Lifestyle project was
studied. Detailed methodology has been previously published. The MetS was defined according to the harmonised
criteria, hypertension according to the JNC criteria, diabetes according to the American Diabetes Association criteria
and echocardiography according to the European Society of Echocardiography guidelines. Results: Normal LV geometry
was found in 80.8%, eccentric hypertrophy 15.9%, concentric hypertrophy 3.2%, concentric remodelling 0.5%.
Logistic regression with MetS as the only independent variable strongly predicted the presence of both concentric
(OR = 4.36 CI 1.84, 10.3 p

Key words: Metabolic syndrome, Left ventricular modelling, Concentric hypertrophy, Eccentric hypertrophy, Cardiovascular disease.


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