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Original Research

BMB. 2018; 3(1): 7-10


Propofol and Seizure Like Activity

Yeşim Çokay Abut, Aykan Gülleroğlu, Ayla Kulaber Sayın, Şeyda Varol, Tayfun Aldemir.




Abstract

Background: In this study, seizure-like activity, injection pain, and the presence of dream after propofol injection were discussed .
Methods and Material: One hundred women who were scheduled for obstetric and gynecologic procedures, were evaluated . Patients were anesthetized with 1mg/kg propofol. The seizure like activity was described as ‘’only left arm’’.’’started from left arm and involved whole body’’ or’’only face’’etc. The intensity of seizure like activity (a brief and involuntary twitching of a muscle or a group of muscles) (SLA) was graded as 0=no SLA, 1=mild SLA-Local Group (only mild fasciculation involving face and/or distal upper and /or lower extremity, focal or involved a part of the body) and 2=severe SLA -Generalized Group (marked movements involving limbs or trunk, generalized to whole body. Operation time, additional doses, time to eye opening, the presence of dream, injection induced pain, if present, seizure like activity descriptions were analyzed .
Statistical analysis
Baseline characteristics were described with mean, standard deviation, rate and frequency. The distribution of variables was controlled with Kolmogorov Smirnow test. Quantitative data’s were compared with ANOVA (Tukey), independent sample t test and Mann Whitney U test. Qualitative data was analyzed with Ki-square test and Fisher test. Statistical analysis was performed using SPSS 21.0 software. A value of p

Key words: Seizure Like Activity, propofol, seizure, GABA , injection induced pain.






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